The discovery of the Fosamax-osteonecrosis connection was first published in the
Journal of Oral and Maxillofacial Surgeons in May 2004. That information
prompted the U.S. Food and Drug Administration to require that all
bisphosphonate labels mention osteonecrosis. Other drug companies updated their
labels to include the warnings in 2004. To date, Merck has not included the
warning on its Fosamax label.
Bisphosphonates remain in the bone indefinitely. Symptoms of bone death in
the jaw include:
- Pain
- Swelling
- Infection of the gums
- Loosening of the teeth
- Poor healing of the gums
- Numbness, or a feeling of heaviness in the jaw
- Exposed bone.
Fosamax can also irritate the esophagus, and care must be taken in order to
avoid such irritation. Recently, researchers discovered that taking Fosamax in
combination with the popular arthritis drug Naproxin may increase the risk of
developing stomach ulcers.
A recent study by the University of Washington has produced evidence that Fosamax may be related to heart irregularities. The study, which was published in the Archives of Internal Medicine, warns of the risk that Fosamax may cause patients to develop atrial fibrillation.
Atrial fibrillation is a disorder which involves chronic irregular heartbeat that can cause shortness of breath, fatigue, fainting, and may create blood clots and lead to stroke.
The study arose after research linked another drug in the same class, Reclast, with causing heart irregularities. Reclast is giving intravenously once a year, while Fosamax is taken in pill form weekly.
The researchers compared the health records of 719 women who had been diagnosed with atrial fibrillation between 2001 and 2004 against those of 966 women who had never had the condition.
Among the atrial fibrillation patients, 6.5 percent had taken Fosamax, compared with 4.1 percent in the other group. Researchers calculated that women who had taken Fosamax were 86 percent more likely to have atrial fibrillation than if they had never taken it. Fosamax users who were diabetic or taking statins to lower cholesterol were among the most likely to develop irregular heartbeat.
Contact your doctor if you have experienced serious side effects associated
with Fosamax. In addition, it may be important to contact an attorney who can
help you protect your legal rights. Please keep in mind that there may be time
limits within which you must commence suit. If you have been injured by Fosamax,
you may be entitled to compensation. For 30 years, the lawyers of Hardison &
Associates have defended those injured or killed because of harmful prescription
drugs. We know that the success of each case depends upon the network of experts
in the medical and legal field who can work with a firm and the case during its
investigation. We look forward to meeting you and discussing your claim. Please
know that we appreciate very much the trust you have placed in our firm.
If you or an acquaintance have been injured by Fosamax, please
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Frequently Asked Questions About Fosamax
